There’s a lot of things that are toxic at high levels but the typical volume avaliable commercially is never going to work, you need some kind of refined to the toxic elements only type of substance, which there’s at least a possibility no one has figured out how to do that refinement, as there’s no sense in it.
Fun fact: alprazolam (Xanax) also has a ridiculously high LD50, about 1220mg/kg in female rats. For a human that weighs 57kg, that works out to 69.5 grams, or about 2.5oz of pure alprazolam. The maximum dose for prescription is 4mg, or .004g; you would need to ingest >17,000 4mg bars of Xanax to consume a fatal dose.
Almost all of the time, “fatal overdoses” of Xanax are in combination with other drugs, like alcohol, which can act as a synergist and depress respiration. But most of the time, you’ll just black out for a few days.
(But. We don’t know that actual LD50 in humans, only in rats and mice. It’s possible that the human LD50 is either lower or higher.)
That’s just because the amount needed to OD is extremely large. You’re more likely to die from other reasons consuming enough marijuana to OD from it.
So? My point still stands that it’s one of the safest mind-altering substances in the world, overdose-wise.
I mean yeah that’s their point, the dose needed to OD on THC is bonkers, so it’s pretty much perfectly safe
There’s a lot of things that are toxic at high levels but the typical volume avaliable commercially is never going to work, you need some kind of refined to the toxic elements only type of substance, which there’s at least a possibility no one has figured out how to do that refinement, as there’s no sense in it.
Fun fact: alprazolam (Xanax) also has a ridiculously high LD50, about 1220mg/kg in female rats. For a human that weighs 57kg, that works out to 69.5 grams, or about 2.5oz of pure alprazolam. The maximum dose for prescription is 4mg, or .004g; you would need to ingest >17,000 4mg bars of Xanax to consume a fatal dose.
Almost all of the time, “fatal overdoses” of Xanax are in combination with other drugs, like alcohol, which can act as a synergist and depress respiration. But most of the time, you’ll just black out for a few days.
(But. We don’t know that actual LD50 in humans, only in rats and mice. It’s possible that the human LD50 is either lower or higher.)