A team led by famed Harvard Medical School anti-aging researcher David Sinclair has just published a paper that shows a mix of chemicals are capable of reversing cellular aging…
It’s Sinclair, stuff around him always gets overly-sensationalized, but skimming though the actual paper… damn, it looks surprisingly promising.
Abstract
A hallmark of eukaryotic aging is a loss of epigenetic information, a process that can be reversed. We have previously shown that the ectopic induction of the Yamanaka factors OCT4, SOX2, and KLF4 (OSK) in mammals can restore youthful DNA methylation patterns, transcript profiles, and tissue function, without erasing cellular identity, a process that requires active DNA demethylation. To screen for molecules that reverse cellular aging and rejuvenate human cells without altering the genome, we developed high-throughput cell-based assays that distinguish young from old and senescent cells, including transcription-based aging clocks and a real-time nucleocytoplasmic compartmentalization (NCC) assay. We identify six chemical cocktails, which, in less than a week and without compromising cellular identity, restore a youthful genome-wide transcript profile and reverse transcriptomic age. Thus, rejuvenation by age reversal can be achieved, not only by genetic, but also chemical means.
and surely everyone will benefit from this right? not just the rich? right?
Depends on if you believe history, which shows technology always spreads, or Hollywood, which would have you believe in conspiracy theories.
I look forward to having a class of rich people who will never die with the rest of us being considered expendable /s
Literally a sub plot of the red mars series.
Also a plot on Altered Carbon. “Meths”, short for methuselahs, rule the world. You get a new body if you can afford it otherwise you get what we give you.
Great, they’ll live to see the consequences of climate change and slowly die anyway
They will move to subterranean refuges and keep their everlasting bodies connected to the metaverse.
So… this is what hell was referring to all along?
- evil people: check
- underground: check
- everlasting: check
metaversetorment: check
I mean, if I had to spend some hundred years in that fun-less wii loby controlled by the Zuck…
Which is a great plot for Black Mirror. Netflix, call me.
Remember not aging doesn’t necessarily mean immortal.
Oh yes, I really look forward to a future where people like Trump or Rupert Murdock live forever.
