Summary

Bryan Johnson, a 46-year-old tech multimillionaire focused on anti-aging, stopped using rapamycin—a supplement he took for five years—after research suggested it might accelerate aging.

Johnson cited side effects like skin infections and glucose issues, as well as findings from a recent study showing rapamycin could worsen epigenetic aging.

Known for extreme anti-aging experiments, Johnson also created the health startup Blueprint, which markets pricey supplements.

His controversial methods, including teenage blood transfusions and genital shock treatments, have raised skepticism about their effectiveness and safety.

  • @[email protected]
    link
    fedilink
    375 months ago

    Watched the documentary with a friend; we were trying to guess his age. We agreed on “decent looking for 55”. He’s 47 lol.

  • @[email protected]
    link
    fedilink
    9
    edit-2
    5 months ago

    I ran across a YouTube video of this guy a couple months ago because a popular YT fitness guy (rock climber) I watch went and interviewed him and did some physical ‘age tests’ with him as well as just talk about his daily routines.

    He doesn’t come across as batshit crazy in the video, but obviously he’s a bit obsessive over this whole thing.

    The funniest part about it was that Magnus (Climber) matched or exceeded him in almost all the physical ‘age tests’ they performed. Of course, Magnus would also outperform most other people in most physical tests but that didn’t make it any less humorous. On the “not as batshit as I imagined” list, he also seemed fairly supportive/genuine of Magnus’ results/abilities during the video.

    https://youtu.be/G7b28Vm9-O0

    • @[email protected]
      link
      fedilink
      55 months ago

      Regular physical activity and spending some time outdoors is more beneficial than injecting weird shit, who knew?

      You can’t fight bad habits with supplements.

      • @[email protected]
        link
        fedilink
        105 months ago

        I don’t believe this guy (Bryan) has a lot of bad habits, his whole life seems to revolve around this life extending plan. I’m not at all defending/justifying him, but he had a pretty good answer regarding what supplements are best when Magnus asked. His response was “The ones you are deficient in”

        Again, as I said above, in the linked video he doesn’t scream “batshit crazy” but just really eccentric!

      • @[email protected]
        link
        fedilink
        65 months ago

        He also exercises and eating healthy though. He isn’t just popping pills and pray for the best.

  • @[email protected]
    link
    fedilink
    35 months ago

    Every fiction writer who described dystopian futures in which the wealthy sought life extension in order to continue amassing control and wealth should pat themselves on the back. Yeah, people and the rulers have always wished for life extending magic, but the dystopia factor is spot on.

  • FundMECFS
    link
    fedilink
    175 months ago

    When you’ve got everything in life and all you want to do is live longer.

    instead of helping the billions living in squalor and dying premature deaths.

    • @[email protected]
      link
      fedilink
      1
      edit-2
      5 months ago

      At this rate, he can likely claim solitude regarding the premature deaths

      Edit: solidarity not solitude. My brain broke this morning.

    • FaceDeer
      link
      fedilink
      65 months ago

      If he hits on an effective anti-aging treatment from his efforts then he’ll help billions that way instead. Pretty much everyone eventually suffers from aging if they live long enough.

      • FundMECFS
        link
        fedilink
        75 months ago

        I applaud your otimism in thinking it will be democratised and not a luxury for wealthy classes.

        • FaceDeer
          link
          fedilink
          65 months ago

          Almost all medications start out as a luxury for wealthy classes.

          When insulin was first discovered as a treatment for diabetes the first Americans to be treated with it back in 1922 were James D. Havens, son of former congressman James S. Havens, and Elizabeth Hughes Gossett, daughter of the US Secretary of State. I can just imagine the Reddit threads at the time decrying how diabetes research was only benefiting the “elites.” But nowadays insulin is manufactured in bulk and anyone can have access to it.

  • @[email protected]
    link
    fedilink
    335 months ago

    this guy sucks. He’s conducting essentially a thousand uncontrolled trials on himself making them all useless unless he dies of a new contraindiction

    • @[email protected]
      link
      fedilink
      175 months ago

      Why does he suck though? Aren’t we all conducting uncontrolled trials on ourselves? Better that, than doing it on other people, right?

      • @[email protected]
        link
        fedilink
        13
        edit-2
        5 months ago

        I think what they meant is even if he finds something that works, the data can’t be trusted, which will heavily delay things like doing it properly.

        • FaceDeer
          link
          fedilink
          95 months ago

          If the tests aren’t being done on anyone else yet then he’s not going to delay anything by trying it himself.

          Frankly, I admire his daring. When people pilot experimental aircraft or climb a mountain nobody’s climbed before they’re considered to be adventurers, he’s doing the pharmaceutical equivalent.

      • @[email protected]
        link
        fedilink
        15 months ago

        He’s doing what all of us are doing which is why the whole article is just ego fellatio for a rich dullard.

  • @[email protected]
    link
    fedilink
    255 months ago

    I watched his video describing a day in his life, sleep at 8pm and wake up at 5am, then take 50 pills, his whole day revolved around preparing for sleep, which he said was the most important thing, so I guess he’s right about that. But just thinking a tiny change in his life, even travelling, will upset this routine, then what, the stress from that routine is probably aging him the most.

    • @[email protected]
      link
      fedilink
      English
      18
      edit-2
      5 months ago

      That’s the thing, he might live a bit longer but at what cost? I would much rather enjoy my life than by a slave to a miserable routine dedicated to promoting longevity that will potentially buy me an extra decade. Like I can just eat a somewhat reasonable diet, exercise, sleep okay and with decent genetics based on my parents and grandparents I will probably make it to at least mid to late 80s, maybe longer if medicine advances. If I had genetics that suggested a strong likelihood that I would die in my 60s I would maybe be more interested

      With this guys routine I could maybe push that to 100ish? I would certainly love to extend my life but not at the cost of it consuming my life. I assume he’s banking on getting to the theoretical max though, which is probably closer to 120ish, and that is substantial but then it’s like a few decades of extremely decreased mobility and mental acuity? Eh

      And of course this all disregards the potential that you get cancer, murdered, car accident, etc.

      • @[email protected]
        link
        fedilink
        105 months ago

        I truly believe he loves doing this so no cost to him as far as mental health/stress goes. Sounds like you are doing most things right so that pretty much covers the 80/20 rule. Johnson is trying to live indefinitely without losing mobility or mental faculties. It’s great that we have someone testing things out and adjusting when things don’t work.

  • Lettuce eat lettuce
    link
    fedilink
    35 months ago

    It would be hilarious if the accelerated aging from the supplement undid all the progress he made from all the other stuff lol.

  • @[email protected]
    link
    fedilink
    14
    edit-2
    5 months ago

    Is this the trickle down economics everyone is talking about? shall we again start selling uranium, platinum etc beverages to the rich?

    He has a team for this?

    “Despite the immense potential from pre-clinical trials, my team and I came to the conclusion…"

    Forget trickle down economics, this is insane just bring the guillotines.

    • Tiefling IRL
      link
      fedilink
      25 months ago

      It’s so completely unfair that idiots like this guy make millions of snake oil “experiments” that don’t even work, but people who dedicate all their time and energy into a labor of love are left to rot

  • @[email protected]
    link
    fedilink
    English
    375 months ago

    Rapamycin

    It’s not just “one of many” it was the big one that has a large online following swearing by it, and lots of idiots taking it.

    Also I can’t see a pic of this guy without thinking of Dennis Reynolds asking if he should wear a mask of his own face.

      • MrPistachios
        link
        fedilink
        English
        35 months ago

        Is he buddy’s with Peter thiel and all the vampires that support trump and want to live forever

    • @[email protected]
      link
      fedilink
      9
      edit-2
      5 months ago

      Every time I think of Dennis Reynolds, I’m reminded of the episode where he tries to sell his car that got stuck in water, and he berates the guy for mentioning how the car isn’t even runnable.

  • @[email protected]
    link
    fedilink
    English
    445 months ago

    Hah, sounds like his “research” is trying it out on himself and deciding he didn’t like it. And now that he doesn’t like it, all of a sudden he finds the research valid. He’s still only listening to opinions he agrees with. What a shallow twat.